Which ocular side effect is reported with chlorpromazine?

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Multiple Choice

Which ocular side effect is reported with chlorpromazine?

Explanation:
Chlorpromazine can cause drug deposition in the cornea. This manifests as fine corneal deposits seen on examination and is related to the dose and duration of therapy. The deposits are usually asymptomatic and tend to be reversible if the drug is reduced or stopped. Other ocular toxicities listed—cataracts, retinal detachment, and glaucoma—are not typical effects of chlorpromazine (retinal changes and cataracts are more commonly linked to other phenothiazines such as thioridazine), so the corneal deposits are the classic ocular finding with this medication.

Chlorpromazine can cause drug deposition in the cornea. This manifests as fine corneal deposits seen on examination and is related to the dose and duration of therapy. The deposits are usually asymptomatic and tend to be reversible if the drug is reduced or stopped. Other ocular toxicities listed—cataracts, retinal detachment, and glaucoma—are not typical effects of chlorpromazine (retinal changes and cataracts are more commonly linked to other phenothiazines such as thioridazine), so the corneal deposits are the classic ocular finding with this medication.

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